Modality-Dependent Impact of Hallucinations on Low-Frequency Fluctuations in Schizophrenia.

ABSTRACT: Prior resting-state functional magnetic resonance imaging (fMRI) analyses have identified patterns of functional connectivity associated with hallucinations in schizophrenia (Sz). In this study, we performed an analysis of the mean amplitude of low-frequency fluctuations (ALFF) to compare resting state spontaneous low-frequency fluctuations in patients with Sz who report experiencing hallucinations impacting different sensory modalities. By exploring dynamics across 2 low-frequency passbands (slow-4 and slow-5), we assessed the impact of hallucination modality and frequency range on spatial ALFF variation. Drawing from a sample of Sz and healthy controls studied as part of the Functional Imaging Biomedical Informatics Research Network (FBIRN), we replicated prior findings showing that pati

SUBMITTER: Hare SM 

PROVIDER: S-EPMC5605256 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature