The Relationship of Intellectual Functioning and Cognitive Performance to Brain Structure in Schizophrenia.

ABSTRACT:

Background

Schizophrenia (SZ) is often characterized by cognitive and intellectual impairment. However, there is much heterogeneity across individuals, suggesting different trajectories of the illness. Recent findings have shown brain volume differences across subgroups of individuals with psychosis (SZ and bipolar disorder), such that those with intellectual and cognitive impairments presented evidence of early cerebral disruption, while those with cognitive but not intellectual impairments showed evidence of progressive brain abnormalities. Our aim was to investigate the relations of cognition and intellectual functioning with brain structure abnormalities in a sample of SZ compared to unaffected individuals.

Methods

92 individuals with SZ and 94 healthy controls part of t

SUBMITTER: Czepielewski LS 

PROVIDER: S-EPMC5605271 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature