Simulating intrafraction prostate motion with a random walk model.

ABSTRACT:

Purpose

Prostate motion during radiation therapy (ie, intrafraction motion) can cause unwanted loss of radiation dose to the prostate and increased dose to the surrounding organs at risk. A compact but general statistical description of this motion could be useful for simulation of radiation therapy delivery or margin calculations. We investigated whether prostate motion could be modeled with a random walk model.

Methods and materials

Prostate motion recorded during 548 radiation therapy fractions in 17 patients was analyzed and used for input in a random walk prostate motion model. The recorded motion was categorized on the basis of whether any transient excursions (ie, rapid prostate motion in the anterior and superior direction followed by a return) occurred in the trace

SUBMITTER: Pommer T 

PROVIDER: S-EPMC5605287 | biostudies-literature | 2017 Jul-Sep

REPOSITORIES: biostudies-literature