Extent of lymphovascular space invasion may predict lymph node metastasis in uterine serous carcinoma.

ABSTRACT:

Objectives

Emerging evidence suggests that extent of lymphovascular space invasion (LVSI) predicts for risk of lymph node metastasis in endometrioid uterine cancers. However, this correlation remains unknown in the setting of uterine serous carcinoma (USC). We sought to examine the association between extent of LVSI and other histopathologic characteristics with risk of nodal metastasis for women with USC.

Materials/methods

Pathological data from all cases of uterine serous carcinoma between July 1998 to July 2015 at our institution were reviewed. Descriptive, univariate, and multivariate logistic regression analysis of selected pathologic features were performed.

Results

88 patients with USC underwent total abdominal or laparoscopic hysterectomy, bilateral salpingo-o

SUBMITTER: Qian Y 

PROVIDER: S-EPMC5605436 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature