C-State: an interactive web app for simultaneous multi-gene visualization and comparative epigenetic pattern search.

ABSTRACT:

Background

Comparative epigenomic analysis across multiple genes presents a bottleneck for bench biologists working with NGS data. Despite the development of standardized peak analysis algorithms, the identification of novel epigenetic patterns and their visualization across gene subsets remains a challenge.

Results

We developed a fast and interactive web app, C-State (Chromatin-State), to query and plot chromatin landscapes across multiple loci and cell types. C-State has an interactive, JavaScript-based graphical user interface and runs locally in modern web browsers that are pre-installed on all computers, thus eliminating the need for cumbersome data transfer, pre-processing and prior programming knowledge.

Conclusions

C-State is unique in its ability to extract a

SUBMITTER: Sowpati DT 

PROVIDER: S-EPMC5606219 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature