Development and validation of QMortality risk prediction algorithm to estimate short term risk of death and assess frailty: cohort study.

ABSTRACT: Objectives To derive and validate a risk prediction equation to estimate the short term risk of death, and to develop a classification method for frailty based on risk of death and risk of unplanned hospital admission.Design Prospective open cohort study.Participants Routinely collected data from 1436 general practices contributing data to QResearch in England between 2012 and 2016. 1079 practices were used to develop the scores and a separate set of 357 practices to validate the scores. 1.47 million patients aged 65-100 years were in the derivation cohort and 0.50 million patients in the validation cohort.Methods Cox proportional hazards models in the derivation cohort were used to derive separate risk equations in men and women for evaluation of the risk of de

SUBMITTER: Hippisley-Cox J 

PROVIDER: S-EPMC5606253 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature