Pharmacogenomics in the treatment of mood disorders: Strategies and Opportunities for personalized psychiatry.

ABSTRACT: Personalized medicine (personalized psychiatry in a specific setting) is a new model towards individualized care, in which knowledge from genomics and other omic pillars (microbiome, epigenomes, proteome, and metabolome) will be combined with clinical data to guide efforts to new drug development and targeted prescription of the existing treatment options. In this review, we summarize pharmacogenomic studies in mood disorders that may lay the foundation towards personalized psychiatry. In addition, we have discussed the possible strategies to integrate data from omic pillars as a future path to personalized psychiatry. So far, the progress of uncovering single nucleotide polymorphisms (SNPs) underpinning treatment efficacy in mood disorders (e.g., SNPs associated with selective serotonin r

SUBMITTER: Amare AT 

PROVIDER: S-EPMC5607053 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature