Antimycobacterial and antimalarial activities of endophytic fungi associated with the ancient and narrowly endemic neotropical plant Vellozia gigantea from Brazil.

ABSTRACT:

Background

Endophytic fungi, present mainly in the Ascomycota and Basidiomycota phyla, are associated with different plants and represent important producers of bioactive natural products. Brazil has a rich biodiversity of plant species, including those reported as being endemic. Among the endemic Brazilian plant species, Vellozia gigantea (Velloziaceae) is threatened by extinction and is a promising target to recover endophytic fungi.

Objective

The present study focused on bioprospecting of bioactive compounds of the endophytic fungi associated with V. gigantea, an endemic, ancient, and endangered plant species that occurs only in the rupestrian grasslands of Brazil.

Methods

The capability of 285 fungal isolates to produce antimicrobial and antimalarial activities wa

SUBMITTER: Ferreira MC 

PROVIDER: S-EPMC5607518 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature