Reproducibility of quantitative structural and physiological MRI measurements.

ABSTRACT:

Introduction

Quantitative longitudinal magnetic resonance imaging and spectroscopy (MRI/S) is used to assess progress of brain disorders and treatment effects. Understanding the significance of MRI/S changes requires knowledge of the inherent technical and physiological consistency of these measurements. This longitudinal study examined the variance and reproducibility of commonly used quantitative MRI/S measurements in healthy subjects while controlling physiological and technical parameters.

Methods

Twenty-five subjects were imaged three times over 5 days on a Siemens 3T Verio scanner equipped with a 32-channel phase array coil. Structural (T1, T2-weighted, and diffusion-weighted imaging) and physiological (pseudocontinuous arterial spin labeling, proton magnetic resonance

SUBMITTER: McGuire SA 

PROVIDER: S-EPMC5607538 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature