Cardiovascular disease and mortality after breast cancer in postmenopausal women: Results from the Women's Health Initiative.

ABSTRACT:

Background

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality among older postmenopausal women. The impact of postmenopausal breast cancer on CVD for older women is uncertain. We hypothesized that older postmenopausal women with breast cancer would be at a higher risk of CVD than similar aged women without breast cancer and that CVD would be a major contributor to the subsequent morbidity and mortality.

Methods

In a prospective Women's Health Initiative study, incident CVD events and total and cause-specific death rates were compared between postmenopausal women with (n = 4,340) and without (n = 97,576) incident invasive breast cancer over 10 years post-diagnosis, stratified by 3 age groups (50-59, 60-69, and 70-79).

Results

Postmenopausal wo

SUBMITTER: Park NJ 

PROVIDER: S-EPMC5608205 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature