Quantitative optical coherence tomography angiography of macular vascular structure and foveal avascular zone in glaucoma.

ABSTRACT:

Objective

The study aimed to evaluate the quantitative characteristics of the macular vessel density (VD) and foveal avascular zone (FAZ) in glaucoma using optical coherence tomography angiography (OCT-A).

Design

Cross-sectional, age- and sex-matched case-control study.

Methods

Fifty-two eyes of 52 patients with primary open angle glaucoma and 52 eyes from 52 healthy participants were recruited retrospectively. OCT-A was performed on a 3 x 3-mm macular region centered on the fovea. OCT-A scans were manually graded to define the FAZ. Parafoveal VD in superficial and deep retina were analyzed in the circular- and quadrant-segmented zone. The FAZ parameters included size, perimeter, and circularity index. The regression analysis among VD and FAZ-related parameters and oc

SUBMITTER: Choi J 

PROVIDER: S-EPMC5608222 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature