The prognostic value of interleukin-17 in lung cancer: A systematic review with meta-analysis based on Chinese patients.

ABSTRACT:

Background

Interleukin-17 (IL-17) plays an important role in cancer progression. Previous studies remained controversial regarding the correlation between IL-17 expression and lung cancer (LC) prognosis. To comprehensively and quantitatively summarize the prognostic value of IL-17 expression in LC patients, a systematic review and meta-analysis were performed.

Methods

We identified the relevant literatures by searching the PubMed, EMBASE, Cochrane Library, SinoMed, China National Knowledge Infrastructure (CNKI) and Wanfang Data databases, up until April 1, 2017. Overall survival (OS), disease free survival (DFS) and clinicopathological characteristics were collected from relevant studies. Pooled hazard ratios (HR) and corresponding 95% confidence intervals (CI) were calculat

SUBMITTER: Wang XF 

PROVIDER: S-EPMC5608354 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature