Synchronizing the transcranial magnetic pulse with electroencephalographic recordings effectively reduces inter-trial variability of the pulse artefact.

ABSTRACT:

Background

Electroencephalography (EEG) can capture the cortical response evoked by transcranial magnetic stimulation (TMS). The TMS pulse provokes a large artefact, which obscures the cortical response in the first milliseconds after TMS. Removing this artefact remains a challenge.

Methods

We delivered monophasic and biphasic TMS to a melon as head phantom and to four healthy participants and recorded the pulse artefact at 5 kHz with a TMS-compatible EEG system. Pulse delivery was either synchronized or non-synchronized to the clock of the EEG recording system. The effects of synchronization were tested at 10 and 20 kHz using the head phantom. We also tested the effect of a soft sheet placed between the stimulation coil and recording electrodes in both human and melon.

R

SUBMITTER: Tomasevic L 

PROVIDER: S-EPMC5608361 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature