Cost-effectiveness of a national enterovirus 71 vaccination program in China.

ABSTRACT:

Background and aims

Enterovirus 71 (EV71) has caused great morbidity, mortality, and use of health service in children younger than five years in China. Vaccines against EV71 have been proved effective and safe by recent phase 3 trials and are now available in China. The purpose of this study was to evaluate the health impact and cost-effectiveness of a national EV71 vaccination program in China.

Methods

Using Microsoft Excel, a decision model was built to calculate the net clinical and economic outcomes of EV71 vaccination compared with no EV71 vaccination in a birth cohort of 1,000,000 Chinese children followed for five years. Model parameters came from published epidemiology, clinical and cost data.

Results

In the base-case, vaccination would annually avert 37,872

SUBMITTER: Wang W 

PROVIDER: S-EPMC5608421 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature