Critical overview of all available animal models for abdominal wall hernia research.

ABSTRACT:

Purpose

Since the introduction of the first prosthetic mesh for abdominal hernia repair, there has been a search for the "ideal mesh." The use of preclinical or animal models for assessment of necessary characteristics of new and existing meshes is an indispensable part of hernia research. Unfortunately, in our experience there is a lack of consensus among different research groups on which model to use. Therefore, we hypothesized that there is a lack of comparability within published animal research on hernia surgery due to wide range in experimental setup among different research groups.

Methods

A systematic search of the literature was performed to provide a complete overview of all animal models published between 2000 and 2014. Relevant parameters on model characteristic

SUBMITTER: Vogels RRM 

PROVIDER: S-EPMC5608772 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature