Acid-base safety during the course of a very low-calorie-ketogenic diet.

ABSTRACT:

Background and aims

Very low-calorie ketogenic (VLCK) diets have been consistently shown to be an effective obesity treatment, but the current evidence for its acid-base safety is limited. The aim of the current work was to evaluate the acid-base status of obese patients during the course of a VLCK diet.

Method

Twenty obese participants undertook a VLCK diet for 4 months. Anthropometric and biochemical parameters, and venous blood gases were obtained on four subsequent visits: visit C-1 (baseline); visit C-2, (1-2 months); maximum ketosis; visit C-3 (2-3 months), ketosis declining; and visit C-4 at 4 months, no ketosis. Results were compared with 51 patients that had an episode of diabetic ketoacidosis as well as with a group that underwent a similar VLCK diet in real life c

SUBMITTER: Gomez-Arbelaez D 

PROVIDER: S-EPMC5608861 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature