The Role of Antibiotics in Modulating Virulence in Staphylococcus aureus.

ABSTRACT: Staphylococcus aureus is often involved in severe infections, in which the effects of bacterial virulence factors have great importance. Antistaphylococcal regimens should take into account the different effects of antibacterial agents on the expression of virulence factors and on the host's immune response. A PubMed literature search was performed to select relevant articles on the effects of antibiotics on staphylococcal toxin production and on the host immune response. Information was sorted according to the methods used for data acquisition (bacterial strains, growth models, and antibiotic concentrations) and the assays used for readout generation. The reported mechanisms underlying S. aureus virulence modulation by antibiotics were reviewed. The relevance of in vitro<

SUBMITTER: Hodille E 

PROVIDER: S-EPMC5608880 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature