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Pediatric clinical features of Mycoplasma pneumoniae infection are associated with bacterial P1 genotype.


ABSTRACT: The present study evaluated the association between different Mycoplasma pneumoniae (M. pneumonia) genotypes and clinical features of pediatric patients. Subjects were children diagnosed with community-acquired pneumonia at the Children's Hospital of Soochow University (Suzhou, China) from January 2012 to December 2013. Clinical and laboratory tests were conducted and clinical samples positive for M. pneumoniae were genotyped by nested-multiplex polymerase chain reaction. Three type I strains and three type II strains were also randomly selected for sequencing. A total of 335 clinical samples positive for M. pneumoniae were obtained. The average age of M. pneumonia-infected pediatric patients was 4.8±3.3 (years). Genotyping results identified 304 positive sample

SUBMITTER: Fan L 

PROVIDER: S-EPMC5609089 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature