Trends for prevalence and incidence of resistant hypertension: population based cohort study in the UK 1995-2015.

ABSTRACT: Objective To estimate the incidence and prevalence of resistant hypertension among a UK population treated for hypertension from 1995 to 2015.Design Cohort study.Setting Electronic health records from the UK Clinical Practice Research Datalink in primary care.Participants 1 317 290 users of antihypertensive drugs with a diagnosis of hypertension.Main outcome measures Resistant hypertension was defined as concurrent use of three antihypertensive drugs inclusive of a diuretic, uncontrolled hypertension (≥140/90 mm Hg), and adherence to the prescribed drug regimen, or concurrent use of four antihypertensive drugs inclusive of a diuretic and adherence to the prescribed drug regimen. To determine incidence, the numerator was new cases of resistant hypertension

SUBMITTER: Sinnott SJ 

PROVIDER: S-EPMC5609092 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature