Occupational Exposure to Talc Increases the Risk of Lung Cancer: A Meta-Analysis of Occupational Cohort Studies.

ABSTRACT:

Objective

Talc is widely used in industrial applications. Previous meta-analyses of carcinogenic effects associated with inhaled talc included publications before 2004, with a lack of data in China, the largest talc-producing country. The safety of workers exposed to talc was unclear due to limited evidence. The objective of this study was to reevaluate the association between inhaled talc and lung cancer.

Setting participants and outcome measures

A meta-analysis was performed to calculate the meta-SMR of lung cancer. We searched the MEDLINE, EMBASE, CNKI, and Wanfang Data databases through March 2017. Data from observational studies were pooled using meta-analysis with random effects models.

Results

Fourteen observational cohort studies (13 publications) were located

SUBMITTER: Chang CJ 

PROVIDER: S-EPMC5610800 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature