A flavoprotein supports cell wall properties in the necrotrophic fungus Alternaria brassicicola.

ABSTRACT:

Background

Flavin-dependent monooxygenases are involved in key biological processes as they catalyze a wide variety of chemo-, regio- and enantioselective oxygenation reactions. Flavoprotein monooxygenases are frequently encountered in micro-organisms, most of which require further functional and biocatalytic assessment. Here we investigated the function of the AbMak1 gene, which encodes a group A flavin monooxygenase in the plant pathogenic fungus Alternaria brassicicola, by generating a deficient mutant and examining its phenotype.

Results

Functional analysis indicates that the AbMak1 protein is involved in cell wall biogenesis and influences the melanization process. We documented a significant decrease in melanin content in the Δabmak1 strain compare

SUBMITTER: Pigne S 

PROVIDER: S-EPMC5611651 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature