Distribution of atherosclerotic stenosis determining early neurologic deterioration in acute ischemic stroke.

ABSTRACT:

Background and purpose

Early neurologic deterioration (END) during the acute stage of stroke is clinically important because of its association with poor outcomes. The purpose of this study was (1) to investigate variables associated with END, (2) to determine the distribution of atherosclerotic stenosis associated with END, and (3) to clarify the relationship between END and clinical outcomes.

Methods

516 patients with acute ischemic stroke were included. The median follow-up period was 31.7 months. END was defined as a ≥2 point increase in the National Institutes of Health Stroke Scale (NIHSS), ≥1 point increase in level of consciousness or motor item of the NIHSS, or the development of any new neurological deficits during the first 72 hours of hospitalization. A signal lo

SUBMITTER: Lee SJ 

PROVIDER: S-EPMC5612689 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature