Morphologically normalized left ventricular motion indicators from MRI feature tracking characterize myocardial infarction.

ABSTRACT: We characterized motion attributes arising from LV spatio-temporal analysis of motion distributions in myocardial infarction. Time-varying 3D finite element shape models were obtained in 300 Controls and 300 patients with myocardial infarction. Inter-individual left ventricular shape differences were eliminated using parallel transport to the grand mean of all cases. The first three principal component (PC) scores were used to characterize trajectory attributes. Scores were tested with ANOVA/MANOVA using patient disease status (Infarcts vs. Controls) as a factor. Infarcted patients had significantly different magnitude, orientation and shape of left ventricular trajectories in comparison to Controls. Significant differences were found for the angle between PC scores 1 and 2 in the endocard

SUBMITTER: Piras P 

PROVIDER: S-EPMC5612925 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature