Ontology highlight
ABSTRACT:
SUBMITTER: Muse ED
PROVIDER: S-EPMC5612952 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Scientific reports 20170925 1
Chest pain is a leading reason patients seek medical evaluation. While assays to detect myocyte death are used to diagnose a heart attack (acute myocardial infarction, AMI), there is no biomarker to indicate an impending cardiac event. Transcriptional patterns present in circulating endothelial cells (CEC) may provide a window into the plaque rupture process and identify a proximal biomarker for AMI. Thus, we aimed to identify a transcriptomic signature of AMI present in whole blood, but derived ...[more]