Dynamic Changes of Genome-Wide DNA Methylation during Soybean Seed Development.

ABSTRACT: Seed development is programmed by expression of many genes in plants. Seed maturation is an important developmental process to soybean seed quality and yield. DNA methylation is a major epigenetic modification regulating gene expression. However, little is known about the dynamic nature of DNA methylation and its effects on gene expression during plant development. Through whole-genome bisulfite sequencing, we showed that DNA methylation went through dynamic changes during seed maturation. An average of 66% CG, 45% CHG and 9% CHH contexts was methylated in cotyledons. CHH methylation levels in cotyledons changed greatly from 6% at the early stage to 11% at the late stage. Transcribed genes were approximately two-fold more likely to be differentially methylated than non-transcribed genes. W

SUBMITTER: An YC 

PROVIDER: S-EPMC5613027 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature