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A protein-protein interaction in magnetosomes: TPR protein MamA interacts with an Mms6 protein.


ABSTRACT: Magnetosomes are membrane-enveloped bacterial organelles containing nano-sized magnetic particles, and function as a cellular magnetic sensor, which assist the cells to navigate and swim along the geomagnetic field. Localized with each magnetosome is a suite of proteins involved in the synthesis, maintenance and functionalization of the organelle, however the detailed molecular organization of the proteins in magnetosomes is unresolved. MamA is one of the most abundant magnetosome-associated proteins and is anchored to the magnetosome vesicles through protein-protein interactions, but the identity of the protein that interacts with MamA is undetermined. In this study, we found that MamA binds to a magnetosome membrane protein Mms6. Two different molecular masses of Mms6, 14.5-kDa and 6.0-k

SUBMITTER: Nguyen HV 

PROVIDER: S-EPMC5613248 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature