Age-related Impairment of Vascular Structure and Functions.

ABSTRACT: Among age-related diseases, cardiovascular and cerebrovascular diseases are major causes of death. Vascular dysfunction is a key characteristic of these diseases wherein age is an independent and essential risk factor. The present work will review morphological alterations of aging vessels in-depth, which includes the discussion of age-related microvessel loss and changes to vasculature involving the capillary basement membrane, intima, media, and adventitia as well as the accompanying vascular dysfunctions arising from these alterations.

SUBMITTER: Xu X 

PROVIDER: S-EPMC5614324 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature