Developmental and adult characterization of secretagogin expressing amacrine cells in zebrafish retina.

ABSTRACT: Calcium binding proteins show stereotypical expression patterns within diverse neuron types across the central nervous system. Here, we provide a characterization of developmental and adult secretagogin-immunolabelled neurons in the zebrafish retina with an emphasis on co-expression of multiple calcium binding proteins. Secretagogin is a recently identified and cloned member of the F-hand family of calcium binding proteins, which labels distinct neuron populations in the retinas of mammalian vertebrates. Both the adult distribution of secretagogin labeled retinal neurons as well as the developmental expression indicative of the stage of neurogenesis during which this calcium binding protein is expressed was quantified. Secretagogin expression was confined to an amacrine interneuron populat

SUBMITTER: Dudczig S 

PROVIDER: S-EPMC5614429 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature