Cost-effectiveness of screening for HIV in primary care: a health economics modelling analysis.

ABSTRACT:

Background

Early HIV diagnosis reduces morbidity, mortality, the probability of onward transmission, and their associated costs, but might increase cost because of earlier initiation of antiretroviral treatment (ART). We investigated this trade-off by estimating the cost-effectiveness of HIV screening in primary care.

Methods

We modelled the effect of the four-times higher diagnosis rate observed in the intervention arm of the RHIVA2 randomised controlled trial done in Hackney, London (UK), a borough with high HIV prevalence (≥0·2% adult prevalence). We constructed a dynamic, compartmental model representing incidence of infection and the effect of screening for HIV in general practices in Hackney. We assessed cost-effectiveness of the RHIVA2 trial by fitting model diagnosis

SUBMITTER: Baggaley RF 

PROVIDER: S-EPMC5614770 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature