Systematic Review of Treatment for Trapped Thrombus in Patent Foramen Ovale.

ABSTRACT:

Background and objectives

Trapped thrombus in patent foramen ovale (PFO) is a rare complication of pulmonary embolism that may lead to tragic clinical events. The aim of this study was to identify the optimal treatment for different clinical situations in patients with trapped thrombus in a PFO by conducting a literature review.

Subjects and methods

A PubMed database search was conducted from 1991 through 2015, and 194 patients (185 articles) with trapped thrombus in a PFO were identified. Patient characteristics, paradoxical embolic events, and factors affecting 60-day mortality were analyzed retrospectively.

Results

Among all patients, 112 (57.7%) were treated with surgery, 28 with thrombolysis, and 54 with anticoagulation alone. Dyspnea (79.4%), chest pain (33.0%),

SUBMITTER: Seo WW 

PROVIDER: S-EPMC5614954 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature