Determination and risk assessment of naturally occurring genotoxic and carcinogenic alkenylbenzenes in basil-containing sauce of pesto.

ABSTRACT: A risk assessment of basil-based pesto sauces containing methyleugenol and related alkenylbenzenes was performed based on their levels detected in a series of pesto sauces available on the Dutch market. The estimated daily intake (EDI) values of alkenylbenzenes as a result of consumption of the different pesto sauces amounted to 1.2-44.3 μg/kg bw for individual alkenylbenzenes, 14.3-43.5 μg/kg bw when adding up the alkenylbenzene levels assuming equal potency, and 17.3-62.9 μg/kg bw when expressed in methyleugenol equivalents using alkenylbenzenes defined toxic equivalency factors (TEF). The margin of exposure approach (MOE), used to evaluate the potential risks, resulted in MOE values that were generally lower than 10000 indicating a priority for risk management when assuming daily consum

SUBMITTER: Al-Malahmeh AJ 

PROVIDER: S-EPMC5615087 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature