Determinants of effective vaccine coverage in low and middle-income countries: a systematic review and interpretive synthesis.

ABSTRACT:

Background

Many children in low and middle-income countries remain unvaccinated, and vaccines do not always produce immunity. Extensive research has sought to understand why, but most studies have been limited in breadth and depth. This study documents existing evidence on determinants of vaccination and immunization and presents a conceptual framework of determinants.

Methods

We used systematic review, content analysis, thematic analysis and interpretive synthesis to document and analyze the existing evidence on determinants of childhood vaccination and immunization.

Results

We documented 1609 articles, including content analysis of 78 articles. Three major thematic models were described in the context of one another. Interpretive synthesis identified similarities an

SUBMITTER: Phillips DE 

PROVIDER: S-EPMC5615444 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature