Sex Differences in Cardiorespiratory Fitness and All-Cause Mortality: The Henry Ford ExercIse Testing (FIT) Project.

ABSTRACT:

Objective

To determine whether sex modifies the relationship between fitness and mortality.

Patients and methods

We included 57,284 patients without coronary artery disease or heart failure who completed a routine treadmill exercise test between 1991 and 2009. We determined metabolic equivalent tasks (METs) and linked patient records with mortality data via the Social Security Death Index. Multivariable Cox regression was used to determine the association between sex, fitness, and all-cause mortality.

Results

There were 29,470 men (51.4%) and 27,814 women (48.6%) with mean ages of 53 and 54 years, respectively. Overall, men achieved 1.7 METs higher than women (P<.001). During median follow-up of 10 years, there were 6402 deaths. The mortality rate for men in each MET

SUBMITTER: Al-Mallah MH 

PROVIDER: S-EPMC5617114 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature