Evaluation of cerebral blood flow change after cigarette smoking using quantitative MRA.

ABSTRACT:

Background and objective

Changes in cerebral blood flow (CBF) immediately after cigarette smoking (CS) are still unclear. Our purpose was to evaluate the hemodynamic changes in each intracranial vessel after CS by using quantitative magnetic resonance angiography (MRA).

Material and methods

Fifteen healthy male smokers less than 45 years old with more than 3 pack-year smoking history were enrolled in this study. The hemodynamic change in the vessels, represented by cerebral flow rate (CFR, ml/s) and flow velocity (FV, cm/s), was quantitatively measured in eleven vascular segments of the brain using phase-contrast MRA. Two sets of data at each vessel before and after CS were statistically analyzed by paired t-test. Three of 15 participants, as a control group, followed all th

SUBMITTER: Song Y 

PROVIDER: S-EPMC5617327 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature