An Intramolecular CAr-H•••O=C Hydrogen Bond and the Configuration of Rotenoids.

ABSTRACT: Over the past half a century, the structure and configuration of the rotenoids, a group of natural products showing multiple promising bioactivities, have been established by interpretation of their NMR and electronic circular dichroism spectra and confirmed by analysis of single-crystal X-ray diffraction data. The chemical shift of the H-6' ¹H NMR resonance has been found to be an indicator of either a cis or trans C/D ring system. In the present study, four structures representing the central rings of a cis-, a trans-, a dehydro-, and an oxadehydro-rotenoid have been plotted using the Mercury program based on X-ray crystal structures reported previously, with the conformations of the C/D ring system, the local bond lengths or interatomic dist

SUBMITTER: Ren Y 

PROVIDER: S-EPMC5617795 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature