Comparative Study on Antistaphylococcal Activity of Lipopeptides in Various Culture Media.

ABSTRACT: Staphylococcus aureus bacteria are one of the leading microorganisms responsible for nosocomial infections as well as being the primary causative pathogen of skin and wound infections. Currently, the therapy of staphylococcal diseases faces many difficulties, due to a variety of mechanisms of resistance and virulence factors. Moreover, a number of infections caused by S. aureus are connected with biofilm formation that impairs effectiveness of the therapy. Short cationic lipopeptides that are designed on the basis of the structure of antimicrobial peptides are likely to provide a promising alternative to conventional antibiotics. Many research groups have proved a high antistaphylococcal potential of lipopeptides, however, the use of different protocols for determination of antimicrobial a

SUBMITTER: Jaskiewicz M 

PROVIDER: S-EPMC5617979 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature