Integrated Metabolomics Assessment of Human Dried Blood Spots and Urine Strips.

ABSTRACT: (1) Background: Interest in the application of metabolomics toward clinical diagnostics development and population health monitoring has grown significantly in recent years. In spite of several advances in analytical and computational tools, obtaining a sufficient number of samples from patients remains an obstacle. The dried blood spot (DBS) and dried urine strip (DUS) methodologies are a minimally invasive sample collection method allowing for the relative simplicity of sample collection and minimal cost. (2) Methods: In the current report, we compared results of targeted metabolomics analyses of four types of human blood sample collection methods (with and without DBS) and two types of urine sample collection (DUS and urine) across several parameters including the metabolite coverage of

SUBMITTER: Drolet J 

PROVIDER: S-EPMC5618320 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature