Versatile telluracycle synthesis via the sequential electrophilic telluration of C(sp²)-Zn and C(sp²)-H bonds.

ABSTRACT: We report herein a new approach for the synthesis of tellurium-bridged aromatic compounds based on the sequential electrophilic telluration of C(sp²)-Zn and C(sp²)-H bonds with tellurium(iv) chlorides. A combination of transition metal-catalyzed (migratory) arylmetalation of alkynes and sequential telluration allows for the expedient construction of a library of functionalized benzo[b]tellurophenes. Furthermore, a variety of heteroarene-fused benzotellurophenes and other novel tellurium-embedded polycyclic aromatics can be readily synthesized from the corresponding 2-iodoheterobiaryls.

SUBMITTER: Wu B 

PROVIDER: S-EPMC5618338 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature