Drivers of antibiotic prescribing in children and adolescents with febrile lower respiratory tract infections.

ABSTRACT:

Background

Knowledge of key drivers for antibiotic prescribing in pediatric lower respiratory tract infection (LRTI) could support rational antibiotic use. Thus, we aimed to determine the impact of clinical and laboratory factors on antibiotic prescribing in children and adolescents with febrile LRTI.

Methods

Pediatric patients from the standard care control group of a randomized controlled trial (ProPAED) investigating procalcitonin guided antibiotic treatment in febrile LRTI were included in a multivariate logistic regression analysis to evaluate the impact of laboratory and clinical factors on antibiotic prescribing.

Results

The standard care control group of the ProPAED study comprised 165 LRTI patients (median age: 2.7 years, range: 0.1-16), out of which 88 (55%)

SUBMITTER: Gotta V 

PROVIDER: S-EPMC5619731 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature