Genomic and Transcriptomic Analysis Reveals Spliced Leader Trans-Splicing in Cryptomonads.

ABSTRACT: Spliced leader trans-splicing (SLTS) is a poorly understood mechanism that is found in a diversity of eukaryotic lineages. In SLTS, a short RNA sequence is added near the 5' ends of the transcripts of protein-coding genes by a modified spliceosomal reaction. Available data suggest that SLTS has evolved many times, and might be more likely to evolve in animals. That SLTS might be more likely to evolve in the context of the generally complex transcriptomes characteristic of animals suggests the possibility that SLTS functions in gene regulation or transcriptome diversification, however no general novel function for SLTS is known. Here, I report SLTS in a lineage of cellularly complex unicellular eukaryotes. Cryptomonads are a group of eukaryotic algae that acquired photosynthetic capacity by

SUBMITTER: Roy SW 

PROVIDER: S-EPMC5619915 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature