Evaluation of the 7^th and 8^th editions of the AJCC/UICC TNM staging systems for lung cancer in a large North American cohort.

ABSTRACT:

Purpose

The new 8^th American Joint Committee on Cancer (AJCC)/International Union for Cancer Control (UICC) lung cancer staging system was developed and internally validated using the International Association for the Study of Lung Cancer (IASLC) database, but external validation is needed. The goal of this study is to validate the discriminatory ability and prognostic performance of this new staging system in a larger, independent non-small cell lung cancer (NSCLC) cohort with greater emphasis on North American patients.

Methods

A total of 858,909 NSCLC cases with one malignant primary tumor collected from 2004 to 2013 in the National Cancer Database (NCDB) were analyzed. The primary coding guidelines of the Collaborative Staging Manual and Coding Instructions fo

SUBMITTER: Yang L 

PROVIDER: S-EPMC5620136 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature