PSY153-MDR, a p12969-DIM-related mega plasmid carrying bla_IMP-45 and armA, from clinical Pseudomonas putida.

ABSTRACT: This work characterized mega plasmid pSY153-MDR, carrying bla_IMP-45 and armA, from a multidrug-resistant (MDR) Pseudomonas putida isolate from the urine of a cerebral infarction patient in China. The backbone of pSY153-MDR was closely related to Pseudomonas plasmids p12969-DIM, pOZ176, pBM413, pTTS12, and pRBL16, and could not be assigned to any of the known incompatibility groups. The accessory modules of pSY153-MDR were composed of 10 individual insertion sequence elements and two different MDR regions, and differed dramatically from the above plasmids. Fifteen non-redundant resistance markers were identified to be involved in resistance to at least eight distinct classes of antibiotics. All of these resistance genes were associated with mobile elem

SUBMITTER: Yuan M 

PROVIDER: S-EPMC5620268 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature