Comparison of chemoradiotherapy with radiotherapy alone for "biopsy only" anaplastic astrocytoma.

ABSTRACT:

Background

It has become increasingly common to incorporate adjuvant chemotherapy with radiotherapy in the treatment of resected anaplastic astrocytoma based on results from recent phase II/III randomized trials. However, whether or not combined chemoradiotherapy is associated with improved survival outcome in patients who undergo "biopsy only" is less clear.

Methods

The US National Cancer Database was used to identify patients with histologically confirmed, biopsy-only anaplastic astrocytoma who received either radiotherapy alone or combined chemoradiotherapy from 2006 through 2014.

Results

In total, 1896 patients with biopsy-only anaplastic astrocytoma were included, among whom 363 (19.1%) received radiotherapy alone and 1533 (80.9%) received combined chemoradiother

SUBMITTER: Wu J 

PROVIDER: S-EPMC5620319 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature