Association of troponin T detected with a highly sensitive assay and cardiac structure and mortality risk in the general population.

ABSTRACT:

Context

Detectable levels of cardiac troponin T (cTnT) are strongly associated with structural heart disease and increased risk of death and adverse cardiovascular events; however, cTnT is rarely detectable in the general population using standard assays.

Objectives

To determine the prevalence and determinants of detectable cTnT in the population using a new highly sensitive assay and to assess whether cTnT levels measured with the new assay associate with pathological cardiac phenotypes and subsequent mortality.

Design, setting, and participants

Cardiac troponin T levels were measured using both the standard and the highly sensitive assays in 3546 individuals aged 30 to 65 years enrolled between 2000 and 2002 in the Dallas Heart Study, a multiethnic, population-based

SUBMITTER: de Lemos JA 

PROVIDER: S-EPMC5621378 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature