Universal sensor array for highly selective system identification using two-dimensional nanoparticles.

ABSTRACT: A typical lock-and-key sensing strategy, relying only on the most dominant interactions between the probe and target, could be too limiting. In reality, the information received upon sensing is much richer. Non-specific events due to various intermolecular forces contribute to the overall received information with different degrees, and when analyzed, could provide a much more powerful detection opportunity. Here, we have assembled a highly selective universal sensor array using water-soluble two-dimensional nanoparticles (nGO, MoS₂ and WS₂) and fluorescent DNA molecules. The array is composed of 12 fluorescently silent non-specific nanoreceptors (2D-nps) and used for the identification of three radically different systems; five proteins, three types of live breast ca

SUBMITTER: Hizir MS 

PROVIDER: S-EPMC5621473 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature