Synthesis and evaluation of MR probes for targeted-reporter imaging.

ABSTRACT: Visualizing disease heterogeneity remains a challenging task since most imaging agents are targeted to a single receptor. We describe the development of an MR platform able to report on multiple molecular events. Enzyme activation and enhanced cellular uptake of this modular probe make it suitable for subsequent targeted-reporter imaging applications.

SUBMITTER: Verma KD 

PROVIDER: S-EPMC5621504 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature