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Physiological adaptations to resistance exercise as a function of age.


ABSTRACT: The impact of resistance exercise training (RE-T) across the life span is poorly defined. To resolve this, we recruited three distinct age cohorts of young (18-28 years; n = 11), middle-aged (45-55 years; n = 20), and older (nonsarcopenic; 65-75 years; n = 17) individuals to a cross-sectional intervention study. All subjects participated in 20 weeks of fully supervised whole-body progressive RE-T, undergoing assessment of body composition, muscle and vascular function, and metabolic health biomarkers before and after RE-T. Individuals also received stable isotope tracer infusions to ascertain muscle protein synthesis (MPS). There was an age-related increase in adiposity, but only young and middle-age groups demonstrated reductions following RE-T. Increases in blood pressure with age were a

SUBMITTER: Phillips BE 

PROVIDER: S-EPMC5621901 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature