Model-based projection of health and economic effects of screening for hepatitis C in Canada.

ABSTRACT:

Background

Because most hepatitis C virus (HCV) infections are asymptomatic and often unrecognized, screening for hepatitis C has been proposed as a plausible public health strategy. We examined the health and economic consequences of a selective one-time hepatitis C screening program for specific populations in the context of current treatment patterns.

Methods

We used a state-transition model to evaluate 2 general strategies: no screening, and screen and treat with direct-acting antiviral agents. We examined these strategies for 4 different target populations (scenarios): 1) asymptomatic people not at high risk for HCV infection, 2) immigrant populations with high prevalence, 3) a birth cohort of people aged 25-64 years and 4) a birth cohort of people aged 45-64 years of a

SUBMITTER: Wong WWL 

PROVIDER: S-EPMC5621948 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature