Methodology to Produce Specimen-Specific Models of Vertebrae: Application to Different Species.

ABSTRACT: Image-based continuum-level finite element models have been used for bones to evaluate fracture risk and the biomechanical effects of diseases and therapies, capturing both the geometry and tissue mechanical properties. Although models of vertebrae of various species have been developed, an inter-species comparison has not yet been investigated. The purpose of this study was to derive species-specific modelling methods and compare the accuracy of image-based finite element models of vertebrae across species. Vertebral specimens were harvested from porcine (N = 12), ovine (N = 13) and bovine (N = 14) spines. The specimens were experimentally loaded to failure and apparent stiffness values were derived. Image-based finite element models were generated reproducing the experimental protocol. A

SUBMITTER: Zapata-Cornelio FY 

PROVIDER: S-EPMC5622177 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature