Usefulness of ^99mTc-dimercaptosuccinic acid renal scan in the diagnosis and follow-up of acute tubulointerstitial nephritis in children.

ABSTRACT:

Background

Symptoms and signs of acute tubulointerstitial nephritis (ATIN) are nonspecific; therefore, renal biopsy is often necessary to clarify the diagnosis. The aim of this study was to evaluate the use of ^99mTc-dimercaptosuccinic acid (DMSA) scintigraphy in the diagnosis and follow-up of ATIN.

Methods

We retrospectively reviewed the charts of five patients (nine renal units) with a median age of 14 years who underwent DMSA scan after a clinical and/or biopsy-proven diagnosis of ATIN. The exam was performed within 1 month after disease onset and repeated at a median time of 12 months after the acute phase.

Results

DMSA renal scans performed during the acute phase allowed the discovery of suggestive findings, including diffuse reduction of the renal upta

SUBMITTER: Vidal E 

PROVIDER: S-EPMC5622892 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature